DoLPHiN: A structural and functional database of natural polysaccharides with health benefits

Title Value
Polysaccharide Arabinogalactan-protein (AGP)
Source Name Lycium barbarum
Weight 50 kDa
Main Glycosidic Bond(s)
Main Chain The backbone of the polysaccharide is made up by repeating disaccharide units of alternating α-D-galactopyranosyl residues, substituted at intervals in the O-6 position with various combinations of mostly α-L-arabinofuranosyl and α-D-galactopyranosyl residues.
Side Chain The side chains exist predominantly as 5-substituted α-L-arabinofuranosyl residues but the complex nature of the side chains is indicated by the presence of 2-substituted, 3-substituted, and 3,5-disubstituted α-L-arabinofuranosyl residues. In addition, 4-substituted α-D-glucopyranosyluronic acid residues were present as internal residues in the side chains. Although α-L-arabinofuranosyl residues terminate most of the side chains, α-D-galactopyranosyl, α-L-rhamnopyranosyl and α-D-glucopyranosyluronic acid residues also fulfill this function.
NMR Information yes
Monosaccharide
glucose 2.49%
mannose 0.31%
galactose 41.75%
xylose 0.31%
arabinose 44.46%
galacturonic acid 7.26%
rhamnose 3.42%
Physiological Functions immunoregulation
Intestinal Microbiota Regulation unknown
Related Diseases (based on ICD-11) 04-Diseases of the immune system
Correlation map Click to view
DOI 10.1016/j.carbpol.2010.12.071
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.