DoLPHiN: A structural and functional database of natural polysaccharides with health benefits

Title Value
Polysaccharide ARP
Source Name Arnebia euchroma
Weight 12.3kDa
Main Glycosidic Bond(s)
β-Galp-(1→6)
α-Arap-(1→3)
α-Arap-(1→5)
α-Glcp-(1→4,6)
α-Manp-(1→3,6)
Main Chain The backbone mainly consisted of Galp residues of 1,6 linkages and Ara residues of 1,5 or 1,3 linkages
Side Chain Ara residues with 1,3, 1,5, and 1,6 linkages, and terminal Glcp and Gal residues." "There is also the possibility of a few 1,4,6 linked Glcp and 1,3,6 linked Manp residues inside the Galp and Ara main chain."
NMR Information yes
Monosaccharide
glucose 11.7%
mannose 6.8%
galactose 53.8%
arabinose 21.3%
rhamnose 4.3%
fucose 2.2%
Physiological Functions ARP has a physiological function of enhancing the proliferation of B cells and T cells, which can stimulate the production of cytokines such as interferon - γ (IFN - γ), enhance the proliferation of B cells and T cells, and significantly affect the activation of macrophages, enhancing the production of TNF - α, IL-6, and IL-1 β.
Intestinal Microbiota Regulation unknown
Related Diseases (based on ICD-11)
Correlation map Click to view
DOI 10.1016/j.ijbiomac.2018.11.238
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.