DoLPHiN: A structural and functional database of natural polysaccharides with health benefits

Title Value
Polysaccharide Ruminococcus gnavus glucorhamnan
Source Name Ruminococcus gnavus
Weight
Main Glycosidic Bond(s)
α-Rhap-(1→2)
α-Rhap-(1→6)
α-Rhap-(1→3)
Main Chain The main chain is composed of rhamnose units linked by 1,3- and 1,2- linkages.
Side Chain The branches consist of two glucose units, with one glucose unit linked through a 1,6- linkage.
NMR Information yes
Monosaccharide
glucose 80.0%
rhamnose 20.0%
Physiological Functions It induces the secretion of the inflammatory cytokine TNFα by dendritic cells, dependent on toll-like receptor 4 (TLR4). .
Intestinal Microbiota Regulation unknown
Related Diseases (based on ICD-11)
Correlation map Click to view
DOI 10.1073/pnas.1904099116
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.