DoLPHiN: A structural and functional database of natural polysaccharides with health benefits

Title Value
Polysaccharide Sulfated galactans
Source Name Codium isthmocladum
Weight
Main Glycosidic Bond(s)
α-Galp-(1→3)
β-Galp-(1→4)
Main Chain The main chain of sulfated galactans in the cell wall of red algae is composed of disaccharide repeating segments in which (1→3)- and (1→4)-linked α,β-D (L)-galactose residues alternately form. For example, the main chain of κ-carrageenan is (1→4)-3,6-anhydro-α-D-galactose-(1→3)-β-D-galactose, etc., and the main chain of agarose is (1→4)-3,6-anhydro-α-L-galactose-(1→3)-β-D-galactose, etc.
Side Chain Sulfate groups, methyl ethers, and pyruvic acid are often combined with these polysaccharides and replace galactose residues at different positions. For example, in κ-carrageenan, the (1→3)-β-linked Galp unit is sulfated at the O - 2 and/or O - 4 positions, and the (1→4)-α-linked Galp unit is sulfated at the O - 2, O - 3, and/or O - 6 positions.
NMR Information unknown
Monosaccharide
Physiological Functions anti-oxidant anti-tumour immunoregulation
Intestinal Microbiota Regulation unknown
Related Diseases (based on ICD-11) Malignant neoplasms,04-Diseases of the immune system
Correlation map Click to view
DOI 10.1007/978-3-642-53971-8_22
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.