| Title |
Value |
| Polysaccharide |
BGR-S2 |
| Source Name |
Avicennia marina |
| Weight |
119kDa
|
| Main Glycosidic Bond(s) |
| α-GalpA-(1→4) |
| α-Rhap-(1→2) |
| α-GalpA-(1→2) |
|
| Main Chain |
It is interspersed with 1,4-linked α-D-galacturonic acid (GalpA), 1,2-linked α-L-rhamnose (Rhap) and 1,2,4-linked α-L-rhamnose residues, that is, [→4-α-D-GalpA (1→2)-α-L-Rhap-(1→)]. |
| Side Chain |
Branched arabinan and galactan side chains are connected at the O-4 position of rhamnose residues by branched chains composed of 1,3-L-arabinose (Araf), 1,5-L-arabinose, 1,3,5-L-arabinose, 1,3-D-galactose (Galp), 1,6-D-galactose, 1,3,6-D-galactose and 1,6-D-glucose (Glcp). |
| NMR Information |
yes
|
| Monosaccharide |
| glucose |
7.77% |
| galactose |
60.19% |
| arabinose |
22.33% |
| rhamnose |
9.71% |
|
| Physiological Functions |
The polysaccharide in the complement determination system shows significant anticomplement activity. Its activity is stronger than that of pectin polysaccharide HAM-3-IIb-II from the stem of Avicennia marina but slightly weaker than that of sodium heparin. It reaches maximum activity at a concentration of 40 μg/ml. The half-hemolytic inhibitory concentration (ICH₅₀) is approximately 16 μg/ml.
|
| Intestinal Microbiota Regulation |
unknown
|
| Related Diseases (based on ICD-11) |
|
| Correlation map |
Click to view |
| DOI |
10.1007/s00217-015-2430-1 |
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.
