| Title |
Value |
| Polysaccharide |
RN1 |
| Source Name |
Panax notoginseng |
| Weight |
20.5kDa
|
| Main Glycosidic Bond(s) |
|
| Main Chain |
It is composed of every four 1,6-linked β-D-galactose (Galp) residues branched by 1,3-linked Galp at the O-3 position. |
| Side Chain |
Mainly connected at the O-3 position of 1,3-linked Galp, containing T/1,5/1,3,5-linked arabinose residues or T-linked galactose residues. |
| NMR Information |
yes
|
| Monosaccharide |
| galactose |
43.7% |
| arabinose |
56.3% |
|
| Physiological Functions |
It can inhibit microvascular formation in BxPC-3 pancreatic cancer cell xenografts in vivo; it exerts an anti-angiogenic effect by inhibiting the BMP2/Smad/Id1 signaling pathway and may become a potential new angiogenesis inhibitor.
|
| Intestinal Microbiota Regulation |
unknown
|
| Related Diseases (based on ICD-11) |
|
| Correlation map |
Click to view |
| DOI |
10.1016/j.carbpol.2014.11.073 |
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.
