DoLPHiN: A structural and functional database of natural polysaccharides with health benefits

Title Value
Polysaccharide GLPs
Source Name Ganoderma lucidum
Weight
Main Glycosidic Bond(s)
Main Chain No relevant information could be found in the literature.
Side Chain No relevant information could be found in the literature.
NMR Information unknown
Monosaccharide
glucose 17.65%
galactose 17.65%
arabinose 64.71%
Physiological Functions It has anti-cancer effects on LoVo human colon cancer cells, manifested as cytotoxicity, inhibition of migration, induction of apoptosis, enhancement of DNA fragmentation, changes in cell morphology, and increased release of lactate dehydrogenase. It mainly exerts its effects through inhibiting migration and inducing apoptosis, and the activation of the Fas/caspase-dependent apoptotic pathway is involved in its cytotoxicity.
Intestinal Microbiota Regulation unknown
Related Diseases (based on ICD-11)
Correlation map Click to view
DOI 10.3892/mmr.2015.4345
Data Source Statement:
The data included in the DoLPHiN database is sourced exclusively from peer-reviewed original publications and presented after normalization.